There are at least two different kinds of schizophrenia, brain scans suggest. The finding may one day lead to more personalized treatment. Nikolaos Koutsouleris of Ludwig Maximilian University of Munich in Germany and his colleagues want to define subtypes of schizophrenia using biology, not symptoms. The team looked at MRI brain scans from 71 people with schizophrenia and 74 people without it. This revealed anatomical differences between people who had the disorder and those who didn't and two subgroups within those with schizophrenia. One subgroup was characterized by a smaller-than-usual volume in the brain's frontal regions. These people had had the condition for less time, and experienced more hallucinations. The other subgroup had more severe symptoms, and differences in more regions of their brains.
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