Mitochondria: masters of epigenetics

• Autores: Marc Tatar, John M. Sedivy
• Localización: Cell, ISSN 0092-8674, Vol. 165, Nº. 5, 2016, págs. 1052-1054
• Idioma: inglés
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• Resumen

  • Accumulating evidence argues that aging exerts a profound influence on epigenetics, and vice versa. A pair of studies by Merkwirth et al. and Tian et al. now provide insights on how mitochondrial stress experienced by C. elegans larvae propagates a specific and persistent epigenetic response that protects adult cells and extends lifespan.