Today, isolating viruses is straightforward--biologists go straight to the genome. But in 1976 it was more craft than science: injecting samples into mice and waiting for odd behavior; putting sample fluids onto cell lines and looking for tell-tale gaps in the tapestry they form, like a hole in a stocking. They did tests to rule out known viruses and viewed the inactivated virus with an electron microscope. That's when they saw it was something new: most viruses are spheres or cubes, but this was like spaghetti. The only other virus with a similar shape was Marburg virus, so they called it "Marburg-like virus". Here, Piot details his experience in the Ebola virus outbreak
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