Radiation-related superficial oral mucoceles: an under-recognized acute toxicity in head and neck cancer patients

• Ana-Carolina Prado-Ribeiro ^[1] ; Alan-Roger Santos-Silva ^[2] ; Karina-Morais Faria ^[1] ; Wagner-Gomes Silva ^[1] ; Luciana-Estevam Simonato ^[3] ; Karina Moutinho ^[1] ; Thais-Bianca Brandão ^[1]
  1. [1] Universidade de São Paulo

     Universidade de São Paulo

     Brasil

     
  2. [2] DDS, MSc, PhD, Oral Diagnosis Department, Semiology Area, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil
  3. [3] DDS, MSc, PhD, Universidade Brasil, Campus Fernandópolis, São Paulo, Brazil

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• Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 23, Nº. 5 (September ), 2018
• Idioma: inglés
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• Resumen

  • Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment.

    Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016.

    Ten (1.2%) patients developed SOMs during radiotherapy, most (80%) of which were men with a mean age of 59.5 years at diagnosis. SOMs mainly affected the floor of the mouth (60%) between the fourth and the sixth weeks of radiation therapy. All lesions were asymptomatic and spontaneously ruptured approximately 9 days after diagnosis.

    Although rare, SOMs may be regarded as an acute oral toxicity of head and neck radiotherapy.