Meiotic Recombination: Genetics’ Good Old Scalpel

• Autores: Shai Slomka, Yitzhak Pilpel
• Localización: Cell, ISSN 0092-8674, Vol. 172, Nº. 3, 2018, págs. 391-392
• Idioma: inglés
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• Resumen

  • In the era of genome engineering, a new study returns to classical genetics to decipher genotype-phenotype relationships in unprecedented throughput and with unprecedented accuracy. Capitalizing on natural variation in yeast strains and frequent meiotic recombination, She and Jarosz (2018) dissect and map to nucleotide resolution, simple and complex determinants of diverse phenotypic traits.