Out with the old

• Autores: Jessica Hamzelou
• Localización: New scientist, ISSN 0262-4079, Nº. 3039, 2015, págs. 30-33
• Idioma: inglés
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• Resumen

  • Hamzelou examines whether purging worn-out cells be all that it takes to stay healthy as people age. The key to the improbable-sounding elixir of youth lies in targeting old, worn-out cells. Young organs are full of cells that divide to replace damaged neighbors. But each only divides a finite number of times. After that they might not die, but instead enter a state called senescence, in which they get bigger and flatter and undergo chemical changes. The same fate awaits cells damaged or stressed by free radicals, reactive molecules created when cells metabolize