The unexpected effects of the combination of antibiotics and immunity

• Autores: Thomas P. Burke
• Localización: Cell, ISSN 0092-8674, Vol. 172, Nº. 5, 2018, págs. 891-893
• Idioma: inglés
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• Resumen

  • β-lactam antibiotics and immune enzymes, including lysozyme, kill bacteria by rupturing the cell wall. Curiously, their combination can select for viable, wall-less bacteria. Kawai and colleagues describe the molecular details regarding the emergence of these forms, illustrating a novel and potentially clinically relevant mechanism by which bacteria escape killing by antibiotics.