J.L. González Fraga, Pilar Sagredo Rodríguez, C. Fraile, Cristina Rupérez Noguer
Se describe un caso de pénfigo vulgar en un perro Pastor alemán, macho, de 8 años. El examen físico mostró lesiones eritematosas, vesiculares y ulcerativas en la cavidad oral, en diversas zonas de la piel y en las uniones cutáneomucosas de la nariz, del prepucio y del ano. A la vista del cuadro clínico, del estudio histopatológico y del test de inmunofluorescencia directa se estableció un diagnóstico de pénfigo vulgar. El tratamiento se basó en la administración oral de prednisona, azatioprina, amoxicilina-ácido clavulánico y vitamina E. Al cabo de tres meses las lesiones remitieron completamente. En la actualidad el animal se encuentra clínicamente controlado con prednisona a una dosis de mantenimiento de 0,5 mg/kg/2 días. * A case of pemphigus vulgaris is described in an 8 year oId, male German Shepherd. Physical examination revealed erythematous, vesicular and ulcerative lesions in the mouth, in different areas of the skin and in the cutaneous-mucosal junctions of the nose, prepuce and anus. Based upon clinical findings, histopathological study, and dírect immunofluorescent test a diagnosis of pemphigus vulgaris was established. Treatment was based on oral administration of prednisone, azathioprine, amoxycillin-clavulanic acid and vitamin E. Complete remission was observed at three months. Presently the animal is clinically controlled with prednisone at a maintenance dose of 0,5 mg/kg on alternate days.
A case of pemphigus vulgaris is described in an 8 year oId, male German Shepherd. Physical examination revealed erythematous, vesicular and ulcerative lesions in the mouth, in different areas of the skin and in the cutaneous-mucosal junctions of the nose, prepuce and anus. Based upon clinical findings, histopathological study, and dírect immunofluorescent test a diagnosis of pemphigus vulgaris was established. Treatment was based on oral administration of prednisone, azathioprine, amoxycillin-clavulanic acid and vitamin E. Complete remission was observed at three months. Presently the animal is clinically controlled with prednisone at a maintenance dose of 0,5 mg/kg on alternate days.
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