Neurons are the inflammatory problem

• Autores: Kevin J. Tracey
• Localización: Cell, ISSN 0092-8674, Vol. 173, Nº. 5, 2018, págs. 1066-1068
• Idioma: inglés
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• Resumen

  • The discovery that reflex neuronal circuits control immunity provided a new mechanistic understanding of infection and injury. Pinho-Ribeiro et al. (2018) report that lethal tissue destruction from streptococcal necrotizing fasciitis (“flesh-eating disease”) occurs because sensory neurons reflexively inhibit frontline immune responses.