If drugs don't work, convert the cancer

• Autores: Michael Slezak
• Localización: New scientist, ISSN 0262-4079, Nº. 3015, 2015, pág. 12
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • A team led by Alex Swarbrick from the Garvan Institute of Medical Research in Sydney, Australia, may have hit on a way of making triple negative cancer toe the line. The team analyzed the DNA of 80 women with triple negative cancer, and found that their tumors produced a lot of a protein called ID4. So, in, mice, the team blocked the 104 gene producing the protein. Their tumors stopped growing and other cancer-related genes got switched on or off. Genes present in cancers that respond to estrogen treatment were activated, making aggressive, resistant breast cancer look like one of the easiest to treat.