Disease heritability studies harness the healthcare system to achieve massive scale

• Joshua C. Denny ^[1] ; Jonathan D. Mosley ^[1]
  1. [1] Vanderbilt University Medical Center

     Vanderbilt University Medical Center

     Estados Unidos

     
• Localización: Cell, ISSN 0092-8674, Vol. 173, Nº. 7, 2018, págs. 1568-1569
• Idioma: inglés
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• Resumen

  • Heritability studies are essential for defining genetic influences on disease risk and trait variability. Polubriaginof et al. show how massive amounts of data contained in electronic health records can be used for heritability studies on hundreds of phenotypes. Mining emergency contact information with comparison to existing gold standards showcases the broad utility of the approach.