The article discusses DNA analyses that provides evidence for interbreeding between Homo sapiens and other human species that may have played a key role in the dominance of human beings. The author discusses a long-held theory, called the Replacement model of human evolution, in which H. sapiens arose in a single region within sub-Saharan Africa and replaced archaic human species, such as Neandertals and H. floresiensis, without interbreeding with them. Topics include DNA studies that challenge this theory, alternative human evolution models, such as the Multiregional Evolution model developed by Milford H. Wolpoff of the University of Michigan and colleagues, and evidence to support the Hybridization model developed by Günter Bräuer of the University of Hamburg, Germany.
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