Rubina Malik, Erica F. Weiss, Reena Gottesman, Jessica Zwerling, Joe Verghese
Objectives To describe the psychometric properties of the Picture‐based Memory Impairment Screen (PMIS) in a multidisciplinary memory disorder center serving an ethnically and educationally diverse community.
Design Cross‐sectional cohort study.
Setting Montefiore Center for Aging Brain (CAB) Participants Individuals with cognitive complaints (N=405; average age 76±10, 66% female).
Measurements A geriatrician or neurologist administered the PMIS, and a neuropsychologist administered the Blessed Information, Memory, and Concentration (BIMC) test and determined whether participants had dementia, mild cognitive impairment (MCI), or subjective cognitive complaints (SCC).
Results Mean PMIS scores were 4.0±2.6 in participants with dementia (n=194), 6.8±1.5 in those with MCI (n= 155), and 7.0±1.8 in those with SCC (n= 56) (p<.001). PMIS scores showed similar significant linear trends when analyzed according to ethnicity, education, sex, and language. The PMIS was negatively correlated with BIMC score (p<.001). The PMIS had positive predictive value of 77%, negative predictive value of 73%, sensitivity of 68%, and specificity of 81% to detect all‐cause dementia in this population of individuals with cognitive complaints.
Conclusion The PMIS is a quick, valid screening tool to identify cognitive impairment in individuals with cognitive complaints that accounts for cultural and educational differences.
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