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Primary burning mouth syndrome: Literature review and preliminary findings suggesting possible association with pain modulation

  • Autores: Cibele Nasri Heir, Diana Shigdar, Deyaaeddin Alnaas, Olga Anna Korczeniewska, Rotem Eliav, Gary M. Heir
  • Localización: Quintessence International, ISSN-e 0033-6572, Vol. 49, Nº. 1, 2018, págs. 49-60
  • Idioma: inglés
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  • Resumen
    • Primary burning mouth syndrome (BMS) is a chronic pain of a burning quality affecting the tongue and intraoral mucosa. Currently, there are no definite diagnostic criteria; therefore, the diagnosis is made by exclusion of potential local and systemic causes that could justify the burning sensation. The etiology behind primary BMS remains unclear; however, the most acceptable theories link primary BMS with neuropathic pain. This article provides a review of primary BMS diagnosis, mechanisms, and treatment with focus on the association of BMS with pain modulation. Preliminary data are presented suggesting a link between primary BMS and a faulty inhibitory pain system.


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