Resumen de Pancreatic cancer's weak spot found
Pancreatic cancer is the most lethal of all common cancers. One reason it is so deadly is that no two cases are genetically the same. So Darren Saunders and colleagues at the Garvan Institute of Medical Research in Sydney, Australia, tried a different approach. As well as looking for variations in the genome of different people's tumors, they also looked at the biological processes at work in the cells. To do this, they switched from using dead tumor cell samples to patient-derived tumor cell lines, in which fresh samples of a person's tumor are grafted onto mice and grown to the required volumes. Growing them in animals makes for more lifelike tumors, and can produce large quantities of tissue for study.
