Neonate-omics: Charting the Unknown Immune Response in Early Life

• Madeleine F. Jennewein ^[1] ; Audrey L. Butler ^[2] ; Galit Alter
  1. [1] The Ragon Institute of MGH, MIT and Harvard
  2. [2] The Ragon Institute o MGH, MIT and Harvard
• Localización: Cell, ISSN 0092-8674, Vol. 174, Nº. 5, 2018, págs. 1051-1053
• Idioma: inglés
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• Resumen

  • The study of neonatal immunology has been hampered by lack of access to infant samples. Novel sample sparing methods and systems-wide approaches have uniquely expanded this field, demonstrating that newborn immunity varies widely but converges over the first 3 months of life. During this important time window, environmental and genetic factors impact the infant immune system and can influence lifelong immunity.