Makin discusses how to banish jet lag. The body's master clock resides in a region of the brain called the suprachiasmatic nucleus. Each neuron in the SCN keeps its own time, but the neurons can synchronize their clocks by sending and receiving signals using a hormone called vasoactive intestinal polypeptide (VIP). When Erik Herzog at Washington University in St Louis MO and colleagues probed the hormone's effects, they discovered that a glut of VIP caused the neurons to lose the ability to synchronize.
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