Vitamin b6 plays an essential role in psoriasis

• Martínez-Navarro, F.J ^[1] ; Martínez-Morcillo, F.J. ^[1] ; Martínez-Menchón, T. ^[2] ; Corbalán-Vélez, R ^[2] ; Pérez-Oliva, A.B ^[1] ; Zon, L.I ^[3] ; Cayuela, M.L ^[2] ; García-Moreno, D. ^[1] ; Mulero, V ^[1]
  1. [1] Universidad de Murcia

     Universidad de Murcia

     Murcia, España

     
  2. [2] Hospital Virgen de la Arrixaca

     Hospital Virgen de la Arrixaca

     Murcia, España

     
  3. [3] Children’s Hospital Boston, Boston, USA.

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• Localización: IV Jornadas Doctorales Escuela Internacional de Doctorado de la Universidad de Murcia (Eidum), 2019, ISBN 978-84-09-09200-0, págs. 197-197
• Idioma: español
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• Resumen

  • Psoriasis is a skin inflammatory disorders that affects 1-3 % of the human population. Although several therapies based in the neutralization of proinflammatory cytokines have been used with relative success, they have important side effects. Therefore, additional treatments are required. Here we report reduced levels of vitamin B6, and increased ones of cystathionine, a marker of vitamin B6 deficiency, in a zebrafish skin inflammation model