Protocol for a prospective, randomised, doubleblind, placebo-controlled study to assess the clinical efficacy of crenotherapy with sulfurous thermal waters in patients with chronic rhinitis / rhinosinusitis

• A. Esteves ^[1] ; J. Viegas ^[1] ; M.R. Pastorinho ^[1] ; O. Lourenço ^[1] ; A.M. Fonseca ^[1] ; E.M. Cardoso ^[1] ; L. Granadeiro ^[1] ; F.A. Arosa ^[1] ; A.J. Santos Silva ^[1] ; P. Padrão ^[2] ; A. Sousa Gomes ^[3] ; L. Taborda-Barata ^[1]
  1. [1] Universidade da Beira Interior

     Universidade da Beira Interior

     Covilhã (Conceição), Portugal

     
  2. [2] Caldas da Felgueira Thermal Spa, Caldas da Felgueira, Portugal
  3. [3] São Pedro do Sul Thermal Spa, São Pedro do Sul, Portugal

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• Localización: Boletín de la Sociedad Española de Hidrología Médica, ISSN 0214-2813, Nº. Extra 1, 2018, págs. 189-190
• Idioma: inglés
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  • Background Chronic rhinitis / rhinosinusitis (CRS) is associated with inflammation of the nasal and perinasal mucosa, with subsequent clinical symptoms.

    Sulfurous (natural mineral) thermal waters (STW) have been used as complementary therapeutic approach to CRS, with studies demonstrating clinical efficacy.

    However, few prospective, randomised, double-blind, placebocontrolled studies have been developed in order to assess clinical efficacy and none has been implemented in Portugal. Furthermore, worldwide, there is scant information of the modulatory effects STW crenotherapy may have on immune-inflammatory aspects underlying CRS.