Raman Spectroscopic Differences between Ephedrine and Pseudoephedrine

• Shu, Tianmin ^[1] ; Yang, Xing ^[2] ; Li, Wenbo ^[1] ; Yao, Xiaojun ^[2]
  1. [1] Department of Criminal Investigation, The Third Research Institute of the Ministry of Public Security. China
  2. [2] College of Chemistry and Chemical Engineering, Lanzhou University.China
• Localización: Journal of forensic sciences, ISSN-e 1556-4029, ISSN 0022-1198, Vol. 64, Nº. 5, 2019, págs. 1482-1485
• Idioma: inglés
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• Resumen

  • Ephedrine (EPH) and pseudoephedrine (PSE) were studied by micro-Raman spectroscopy and UV resonance Raman spec-troscopy excited at 785 and 360 nm, respectively. Raman bands at approximately 245 and 410 cm-1 for ephedrine have apparent differencesfrom the same bands at approximately 215, 265, 350, 450, and 555 cm-1 for pseudoephedrine, and these differences can be applied to distin-guish between EPH and PSE. Additionally, density functional theory was used for the Raman calculations to obtain results identical to theexperimental spectra. This work is expected to expand the applications of Raman spectroscopy in forensic science.