Master key opens door to longer life

• Autores: Douglas Heaven
• Localización: New scientist, ISSN 0262-4079, Nº. 2915, 2013, págs. 8-9
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Heaven talks about brain's control center for ageing can be manipulated to extend lifespan in mice. The several new drug targets that, if not quite an elixir of youth, may at least delay the onset of age-related disease. While investigating ageing processes in the brain, Dongsheng Cai and his colleagues noticed that ageing mice produce increasing levels of nuclear factor kB (NF-kB)--a protein complex that plays a major role in regulating immune responses. NF-kB is barely active in the hypothalamus of three to four-month-old mice but becomes very active in old mice, aged 22 to 24 months.