Catching up with Lyme Disease Antigenic Variation Computationally

• Autores: Steven J. Norris
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 26, Nº. 8, 2018, págs. 644-645
• Idioma: inglés
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• Resumen

  • The spirochetes that cause Lyme disease have an elaborate antigenic variation system that produces millions of variants, thus evading the immune response. Verhey et al. have applied next-generation sequencing and computational analysis to gain new insights into how these bacteria keep ‘one step ahead’ of elimination by the host.