The New Kid on the Block: A Specialized Secretion System during Bacterial Sporulation
- Autores: Cécile Morlot, Christopher D.A. Rodrigues
- Localización: Trends in microbiology, ISSN 0966-842X, Vol. 26, Nº. 8, 2018, págs. 663-676
- Idioma: inglés
- Enlaces
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Resumen
The transport of proteins across the bacterial cell envelope is mediated by protein complexes called specialized secretion systems. These nanomachines exist in both Gram-positive and Gram-negative bacteria and have been categorized into different types based on their structural components and function. Interestingly, multiple studies suggest the existence of a protein complex in endospore-forming bacteria that appears to be a new type of specialized secretion system. This protein complex is called the SpoIIIA-SpoIIQ complex and is an exception to the categorical norm since it appears to be a hybrid composed of different parts from well-defined specialized secretion systems. Here we summarize and discuss the current understanding of this complex and its potential role as a specialized secretion system.
