Hybrid ameloblastoma and central giant cell lesion: challenge of early diagnosis

• Rúbia-Teodoro Stuepp ^[1] ; Luiz-Henrique-Godoi Marola ^[2] ; Filipe Modolo ^[3] ; Rogério Gondak ^[3]
  1. [1] Postgraduate Program in Dentistry, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
  2. [2] Bucomaxillofacial Residence Program, University Hospital, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil
  3. [3] Department of Pathology, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil

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• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 12, Nº. 2 (February), 2020, págs. 204-208
• Idioma: inglés
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• Resumen

  • Hybrid lesions encompass the occurrence of different entities in one lesion. A 67-year-old woman was referred to the Oral and Maxillofacial Surgery Service for treatment of mandibular Central Giant Cell Lesion (CGCL) previously diagnosed. Intraoral examination revealed edentulism and a painless swelling extending from the alveolar ridge to the buccal vestibule with hard consistency covered by normal mucosae, with unknown duration. Panoramic radiograph revealed a large, multilocular and well-defined radiolucent lesion extending from the region of left mandibular lateral incisor teeth to right mandibular first molar with no evidence of osseous perforation. Initially, a treatment with intralesional injection of corticosteroids was performed. After 18 months of treatment, an increase in size of the osteolytic lesion was noted. An incisional biopsy was carried out and the microscopic examination revealed a unicystic ameloblastoma associated to CGCL. It was performed marsupialization and later the enucleation of residual lesion. The follow-up remains being performed.