Chemical Targeting and Manipulation of Type III Secretion in the Phytopathogen Xanthomonas campestris for Control of Disease

• Le Zhou ^[1] ; Cheng Wang ^[1] ; Guo-Hua Wang ^[1] ; Zai-Wa Wei ^[1] ; Qiu-Xia Fu ^[1] ; Xiao-Hong Hang ^[1] ; Mei Yang ^[1] ; Bo-Le Jiang ^[1] ; Ji-Liang Tang ^[1]
  1. [1] Guangxi University

     Guangxi University

     China

     
• Localización: Applied and Environmental Microbiology, ISSN 0099-2240, Vol. 86, Nº 3, 2020
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • The bacterium Xanthomonas campestris pv. campestris is known to cause black rot disease in many socioeconomically important vegetable crops worldwide. The management and control of black rot disease have been tackled with chemical and host resistance methods with variable success. This has motivated the development of alternative methods for preventing this disease. Here, we identify a set of novel small molecules capable of inhibiting X. campestris pv. campestris virulence, which may represent leading compounds for the further development of antivirulence agents that could be used in the control of black rot disease.