Nozzle pressure analysis of several hydrogel on extrusion-based bioprinting using computational fluid dynamics

• Juan Carlos Gómez Blanco ^[1] ; Enrique Mancha Sánchez ^[1] ; Diego Torrejón Martín ^[2] ; Juan Pablo Carrasco Amador ^[2] ; Francisco Miguel Sánchez Margallo ^[1] ; José Blas Pagador Carrasco ^[1]
  1. [1] Centro de Cirugía de Mínima Invasión

     Centro de Cirugía de Mínima Invasión

     Cáceres, España

     
  2. [2] Universidad de Extremadura

     Universidad de Extremadura

     Badajoz, España

     
• Localización: XXXIX Jornadas de Automática: actas. Badajoz, 5-7 de septiembre de 2018 / coord. por Inés Tejado Balsera, Emiliano Pérez Hernández, Antonio José Calderón Godoy, Isaías González Pérez, Pilar Merchán García, Jesús Salvador Lozano Rogado, Santiago Salamanca Miño, Blas Manuel Vinagre Jara, 2018, ISBN 978-84-9749-756-5, págs. 737-741
• Idioma: inglés
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• Resumen

  • Extrusion bioprinting is an additive manufacturing technology with huge possibilities in the creation of engineered tissues. There are many researches about materials, cells and their interrelation. Nevertheless, there are not many researches about how the mechanics affect to cellular viability. In this way, we have done CFD simulations to check how the viscosity of materials can affect the pressure distribution in the tip of a nozzle. These results will be updated, in future works, with simulations of several materials and geometries.