Lysis of a Lactococcus lactis Dipeptidase Mutant and Rescue by Mutation in the Pleiotropic Regulator CodY

• Chenxi Huang ^[1] ; Jhonatan A. Hernandez-Valdes ^[1] ; Oscar P. Kuipers ^[1] ; Jan Kok ^[1]
  1. [1] University of Groningen

     University of Groningen

     Países Bajos

     
• Localización: Applied and Environmental Microbiology, ISSN 0099-2240, Vol. 86, Nº 8, 2020
• Idioma: inglés
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• Resumen

  • Precise control of peptidoglycan synthesis is essential in Gram-positive bacteria for maintaining cell shape and integrity as well as resisting stresses. Although neither the dipeptidase PepV nor alanine is essential for L. lactis MG1363, adequate availability of either ensures proper cell wall synthesis. We broaden the knowledge about the dipeptidase PepV, which acts as a linker between nitrogen metabolism and cell wall synthesis in L. lactis.