Kill switch could make cells self-destruct if they go rogue

• Autores: Michael Le Page
• Localización: New scientist, ISSN 0262-4079, Nº. 3271, 2020, pág. 15
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • A genetic tweak can make cells destroy themselves in the face of CRISPR gene editing, a trick with a variety of possible uses. CRISPR can be used to easily introduce changes to the DNA of living cells. It is a useful technique, but it would be handy to be able to make some cells CRISPR-resistant. For example, there is interest in storing information in DNA inside cells, and rendering some of them uneditable by CRISPR could enable us to make "read-only" reference copies. Here, La Page discusses a method developed by George Church at Harvard University to make human cells CRISPR-proof.