Current data on the localization of neuropeptide Y-related peptides in the hypothalamo-pituitaryadrenal gland (HPA) axis as well as the effects of these peptides on the function of cells comprising HPA axis are presented and discussed. The action of neuropeptide Y. peptide YY, and pancreatic polypeptide on HPA axis are evaluated. Moreover, we report the presence of pancreatic polypeptide immunoreactivity in subset of chromaffin cells in the medulla of rat adrenal gland.
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