Infective Endocarditis in Persons Who Use Drugs: Epidemiology, Current Management, and Emerging Treatments

• Autores: Asher Schranz, Joshua A Barocas
• Localización: Infectious disease clinics of North America, ISSN 0891-5520, Vol. 34, Nº. 3, 2020 (Ejemplar dedicado a: Infectious Disease Complications of Opioid Use and Other Substance Use Disorders), págs. 479-493
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Infective endocarditis associated with injection drug use (IDU-IE) is markedly increasing in the United States and Canada. Long-term outcomes are dismal and stem from insufficient substance use disorder treatment. In this review, we summarize the principles of antimicrobial and surgical management for infective endocarditis associated with injection drug use. We discuss approaches to opioid use disorder care and harm reduction in the inpatient setting and review opportunities to address preventable infections among persons injecting drugs. We highlight barriers to implementing optimal treatment and consider novel approaches that may reshape infective endocarditis associated with injection drug use treatment in coming years.