Severe colon ischemia in patients with severe coronavirus-19 (COVID-19)

• Ana Almeida Vargas ^[1] ; Víctor Valentí ^[1] ; Carlos Sánchez Justicia ^[1] ; Fernando Martínez Regueira ^[1] ; Pablo Martí Cruchaga ^[1] ; Juan Luján Colás ^[1] ; Daniel Aliseda Jover ^[1] ; Sara Esteban Gordillo ^[1] ; Javier A. Cienfuegos ^[1] ; Fernando Rotellar Sastre ^[1]
  1. [1] Clínica Universitaria de Navarra

     Clínica Universitaria de Navarra

     Pamplona, España

     
• Localización: Revista Española de Enfermedades Digestivas, ISSN-e 2340-4167, ISSN 1130-0108, Vol. 112, Nº. 10, 2020, págs. 784-787
• Idioma: inglés
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• Resumen

  • COVID-19 is associated with severe coagulopathy. We present three cases of colonic ischemia that can be attributed to the hypercoagulable state related with SARS-CoV2 and disseminated intravascular coagulation. Three males aged 76, 68 and 56 with respiratory distress presented episodes of rectal bleeding, abdominal distension and signs of peritoneal irritation. Endoscopy (case 1) and computed tomography angiography revealed colonic ischemia. One patient (case 2) in which a computed tomography (CT) scan showed perforation of the gangrenous cecum underwent surgery. D-dimer levels were markedly increased (2,170, 2,100 and 7,360 ng/ml) in all three patients. All three patients died shortly after diagnosis.