Resumen de Outcomes of drug-induced acute pancreatitis: a ten-year experience of an academic center

Rubén Sánchez Aldehuelo, Ana García García de Paredes, Diego Rojo Lázaro, Antonio Jesús Martínez Ortega, Irene García de la Filia Molina, Sergio López Durán, Miguel Ángel Rodríguez Gandía, Antonio López Sanromán, Agustín Albillos Martínez

• Background: drug-induced pancreatitis is an unexplored entity. Methods: a retrospective cohort study was performed at a referral center. Patients with drug-induced acute pancreatitis between 2008 and 2018 were included. Baseline patient characteristics, involved drugs, clinical course and recurrence were analyzed. Results: drug-induced pancreatitis represented 2.8 % of acute pancreatitis (47/1,665) and 18 different drugs were involved (thiopurines 61.8 %). The latency period was less than one month in 87.2 % of cases. Pancreatitis was mild in 89.3 % and recurrence risk was 2.3 %. Conclusion: drugs are a rare cause of pancreatitis, which mostly occurs within the first month of treatment, is usually mild and is associated with a low risk of recurrence.