Nontraditional Aspects of Sporadic Primary Hyperparathyroidism
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Marcella Walker [1] ; Shonni J. Silverberg [2]
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[1] Division of Endocrinology, Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA
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[2] Division of Endocrinology, Department of Medicine, Columbia University, Columbia University Irving Medical Center, New York, NY 10032, USA
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- Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 50, Nº. 4, 2021 (Ejemplar dedicado a: Hypercalcemia), págs. 629-647
- Idioma: inglés
- Texto completo no disponible (Saber más ...)
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Resumen
Nontraditional aspects of primary hyperparathyroidism refer to the condition's rheumatic, gastrointestinal, cardiovascular, and neuropsychological effects. Although gastrointestinal and rheumatic symptomatology were features of classical primary hyperparathyroidism, they do not seem to be a part of the modern presentation of primary hyperparathyroidism. In contrast, neuropsychological symptoms such as altered mood and cognition, as well as cardiovascular disease, have been associated with the form of primary hyperparathyroidism seen today, but the relationship is not clearly causal. Evidence does not support reversibility after parathyroidectomy and therefore none of the nontraditional manifestations are considered sole indications for recommending surgery at this time.
