Abraham Portillo Pineda, Ma. Auxilio Núñez Olivares, Benigno Figueroa Núñez, Alonso Carlos Gómez, Oliva Mejía Rodríguez
Objetivo: identificar la relación de Acantosis nigricans (an) con obesidad y Resistencia a la Insulina (ri) en niños y adolescentes de 10 a 16 años. Material y métodos: estudio descriptivo, transversal. Previa firma de consentimiento informado se incluyó una muestra no probabilística por conveniencia de 146 niños y adolescentes de entre 10 a 16 años de mayo 2008 a junio 2009; se categorizaron en dos grupos: 69 con an y 77 sin an. Se evaluaron las siguientes variables: glucosa e insulina en ayuno y postprandial, triglicéridos, colesterol, lipoproteínas de alta densidad, presión arterial, peso, talla, Índice de Masa Corporal (imc) y composición corporal; posteriormente se calculó el índice homa (modelo de evaluación de la homeostasis). Se establecieron puntos de corte de acuerdo con atp iii (Adult Treatment Panel), las diferencias entre grupos se analizaron con t de Student. Resultados: la edad de la muestra estudiada no presentó diferencias significativas entre adolescentes con an 12.9±1.9 y sin an 13.05±2.1. Se encontraron diferencias significativas en las siguientes variables: peso: an 66.7±14.1, sin an 60.53±15.7 p=.01; imc: an 27.5±3.9, sin an 24.8±7.3 p=.008; homa: an 3.9±2.5, sin an 2.8±3.2 p=.034; colesterol: an 173.5±32.8, sin an 160.9±37.6 p=.03; triglicéridos: an 150.9±63.3, sin an 119.5±66.5 p=.004; lipoproteínas de alta densidad (hdl): an 35.1±7.3, sin an 41.0±8.9 p=.00; Presión Arterial Sistólica (pas): an 115.7±11.6, sin an 111.74±10.4 p=.02; Presión Arterial Diastólica (pad): an 74.0±9.5, sin an 69.19±8.5 p=.001. Conclusiones: 100% de los niños y adolescentes con an presentaron alguna alteración ya sea clínica o bioquímica, en estos adolescentes es imperativo la evaluación clínica completa y su atención médica inmediata.
Objective: to identify the relation of Acantosis nigricans (an) with obesity and Insulin Resistance (ir) in children and adolescents from 10 to 16 years old. Material and methods: descriptive, cross sectional study. After signing an informed consent which included a non random sample of convenience of 146 children and adolescents aged 10 to 16 from May 2008 to June 2009; the sample was categorized in two groups: 69 with an and 77 without an. The following variables were assessed: glucose and insulin in fasting and postprandial triglycerides, cholesterol, high density lipoprotein, blood pressure, weight, height, Body Mass Index (bmi) and body composition; subsequently the homa index (Homeostasis Model Assessment) was calculated. Cutoff points were established according to the atp iii (Adult Treatment Panel), and differences between groups were analyzed with the Student t test. Results: the age of the sample studied did not show important differences between adolescents with an 12.9±1.9 and without an 13.05±2.1. Important differences were found in the following variables: weight: an 66.1±14.1, without an 60.53±15.7 p=.01; bmi: an 27.5±3.9, without an 24.8±7.3 p=.008; homa: an 3.9±2.5, without an 2.8±3.2 p=.034; cholesterol: an 173.5±32.8, without an 160.9±37.6 p=.03; triglycerides: an 150.9±63.3, without an 119.5 ± 66.5 p=.004; High Density Lipoprotein (hdl): an 35.1±7.3, without an 41.0±8.9 p=.00; Systolic Blood Pressure (sbp): an 115.7±11.6, without an 111.74±10.4 p=.02; Diastolic Blood Pressure (dbp): an 4.0±9.5, without an 69.19±8.5 p=.001. Conclusions: 100% of the children and adolescents with an presented some changes either clinical or biochemical, in these adolescents it is imperative to have a complete clinical evaluation and an immediate medical care.
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