The 20th anniversary of the innovation district of Barcelona, the 22@Barcelona, provides the rationale for this special issue. Key actors in the academia, organisations and institutions from several innovation districts around the world, have joined this celebration project that has materialized in the collection of articles that conform “Districts of Innovation in the World”. The result is a unique compilation of experiences, analysis and evaluations that evidence the relevance of innovation districts as tools for urban, economic and social development but also as urban cores of production of technology and innovation. Benefiting from years of exchange of ideas and mutual collaboration, this special issue offers, from an evolutionary perspective, an analysis of the transitions, adaptations and mutations that innovation districts have experienced around the world.
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