Hipertrigliceridemia en pancreatitis aguda: reporte de tres casos con sus tratamientos

• Nadia Mileva Semrik ^[1] ; Pablo Lucero ^[1] ; Ignacio Gutiérrez Magaldi ^[1]
  1. [1] Ciencias de la Salud
• Localización: Revista Methodo: Investigación Aplicada a las Ciencias Biológicas, ISSN-e 2545-8302, Vol. 7, Nº. 3, 2022, págs. 269-273
• Idioma: español
• Títulos paralelos:
  • Hypertriglyceridemia in acute pancreatitis: report of three cases with their treatments
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• Resumen
  • español

    La pancreatitis aguda (PA) es un proceso inflamatorio, agudo y reversible del páncreas. Presenta múltiples etiologías, entre ellas la hipertrigliceridemia como tercera causa más frecuente. Suele generar entre el 1 al 14% de todos los casos de PA. El riesgo incrementa de manera directamente proporcional a los niveles de triglicéridos séricos cuando éstos superan los 500 mg dL.

    Es importante tener presente esta etiología ya que se asocia a un mal pronóstico. A continuación, se presentan tres casos clínicos, dos varones y una mujer, jóvenes entre 35 y 41 años de edad.

    Se narran las diferentes evoluciones y tratamientos utilizados, sus respuestas según el valor de triglicéridos, teniendo en cuenta que no existe un tratamiento estándar para el manejo de la enfermedad por su poca frecuencia.

  • English

    Acute pancreatitis (AP) is an acute and reversible inflammatory process of the pancreas. AP is associated with multiple etiologies, including hypertriglyceridemia which is responsible of 1% to 14% of all cases of AP. The risk of AP associated with hypertriglyceridemia increases directly proportionally to serum triglyceride levels, especially when exceeding 500 mg / dL.

    It is important to keep this etiology in mind as it is associated with a poor prognosis. Presenting in the following clinical cases, two men and one woman, young people between 35 and 41 years of age.

    Its importance lies in the fact that there are three clinical syndromes caused by hypertriglyceridemia, but with different antecedents, clinical evolution and treatment. Currently, various publications agree that the increase in prevalent diseases: hypertension, diabetes and obesity, are related to familial or non-familial hypertriglyceridemia and this will undoubtedly modify the percentage of BP due to a serum level of triglycerides as well as the increase in cirrhosis due to NASH.

    The different evolutions and treatments used with their responses are observed according to the triglyceride value, taking into account that there is no standard treatment for the management of the disease due to its infrequency 2. Therefore, cases will be shown to add to the evidence in this treatment. In addition, the prolongation of hospitalizations can be observed due to complications secondary to this disease.