Resumen de Un caso de Sarcoidosis Multisistémica peculiar

Ana Gorgulho, Ana Paula Antunes, Carolina Sequeira, Anabela Salgueiro Marques

• Sarcoidosis is a chronic multisystemic disease of unknown etiology, characterized by the formation of non-caseous granulomas, most commonly with lung, intrathoracic lymph node, skin and ocular involvement. We present the case of a 69-year-old male with hyperthyroidism due to a toxic nodule who underwent a thyroidectomy but kept losing weight. Afterwards he developed photopsias, hepatosplenomegaly and pancytopenia.

  Exams revealed non-caseous granulomatous involvement of thyroid, eye, liver and bone marrow. Corticosteroid therapy was initiated with overall improvement but the patient developed hypercortisolism and hyperglycemia and did not tolerate steroid taping. Azathioprine was started, allowing improvement with low dose steroids.

  This case illustrates an infrequent case of sarcoidosis with exclusive extra-thoracic disease, highlighting the rare bone marrow and thyroid involvement causing an unspecific presentation