Colombia
Ante la perspectiva de que millones de personas en todo el mundo mueran por enfermedades crónicas no transmisibles, la comunidad científica reconoce el impacto en la salud mental de un diagnóstico de enfermedad crónica. Por eso, este estudio se propone describir la prevalencia de las enfermedades crónicas no transmisibles y los biomarcadores asociados al riesgo suicida. Para ello, se seleccionaron 27 artículos publicados entre el 2014 y 2020 de diversas bases de datos. Se encontró que las enfermedades más frecuentes asociadas al riesgo de suicidio fueron cáncer, hipertensión, enfermedad pulmonar obstructiva crónica, enfermedades inflamatorias intestinales, neumoconiosis y ooforectomía. En cuanto a los biomarcadores, se encontró que hay genes relacionados con el riesgo suicida en pacientes con enfermedades crónicas como el cáncer, enfermedades neurodegenerativas, diabetes y obesidad/colesterol. Otros factores de riesgo suicida se relacionaron con el inicio de la enfermedad en la adolescencia, el someterse a procedimientos quirúrgicos, quimioterapias, ser un hombre mayor de 65 años y ser soltero.
Against the backdrop of the millions of people dying worldwide from chronic noncommunicable diseases, the scientific community must recognize the mental health impact of a chronic disease diagnosis. Consequently, the aim of this study is to describe the prevalence of chronic noncommunicable diseases and biomarkers associated with suicide risk. To this end, 27 articles published between 2014 and 2020 were selected from various databases. The most frequent diseases associated with suicide risk were found to be cancer, hypertension, chronic obstructive pulmonary disease, inflammatory bowel disease, pneumoconiosis and oophorectomy. As for biomarkers, genes were found to be associated with suicide risk in patients with chronic diseases such as cancer, neurodegenerative diseases, diabetes and obesity/cholesterol. Other risk factors for suicide were related to onset of the disease in adolescence, undergoing surgical procedures, chemotherapy, being a male over 65, and being single. The most prevalent diseases related to suicide risk are: cancer, hypertension, COPD, inflammatory bowel diseases, pneumoconiosis and oophorectomy. The biomarkers present in relation to suicidal risk for cancer are: AK2, PTEN, LHFP and SATI; for neurodegenerative diseases and diabetes CLN5; and obesity/cholesterol: ABCA-I. Other suicide risk factors: onset of NCD in adolescence, surgical procedures, chemotherapies, men older than 65 years, and single patients. NCDs related to suicidal risk are cancer with specific biomarkers, as in neurodegenerative diseases and diabetes, suicidal ideation is more present in patients with NCDs with association to social and psychological factors
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