MiRNAs in renal cell carcinoma

• Jesús Miranda-Poma ^[2] ; Lucía Trilla-Fuertes ^[3] ; Elena López-Camacho ^[3] ; Andrea Zapater-Moros ^[3] ; Rocío López-Vacas ^[3] ; María Isabel Lumbreras-Herrera ^[3] ; Ana Pertejo-Fernandez ^[1] ; Juan Ángel Fresno-Vara ^[3] ; Enrique Espinosa-Arranz ^[1] ; Angelo Gámez-Pozo ^[3] ; Álvaro Pinto-Marín ^[1]
  1. [1] Hospital Universitario La Paz

     Hospital Universitario La Paz

     Madrid, España

     
  2. [2] Oncología Médica, Hospital Universitario Quirónsalud, Madrid, España
  3. [3] Laboratorio Oncología Molecular, Hospital Universitario La Paz-IdiPAZ, Madrid, España

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• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 24, Nº. 11 (November), 2022, págs. 2055-2063
• Idioma: inglés
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• Resumen

  • MicroRNAs (miRNAs) are small RNA sequences that act as post-transcriptional regulatory genes to control many cellular processes through pairing bases with a complementary messenger RNA (mRNA). A single miRNA molecule can regulate more than 200 different transcripts and the same mRNA can be regulated by multiple miRNAs. In this review, we highlight the importance of miRNAs and collect the existing evidence on their relationship with kidney cancer.