Physiology Reconfigured: how Does Bariatric Surgery Lead to Diabetes Remission?

• Vance L. Albaugh ^[2] ; Christopher Axelrod ^[1] ; Kathryn P. Belmont ^[1] ; John P. Kirwan ^[1]
  1. [1] Louisiana State University

     Louisiana State University

     Estados Unidos

     
  2. [2] Metamor Institute, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA b Integrative Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA 70808, USA
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 52, Nº. 1, 2023, págs. 49-64
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Bariatric surgery improves glucose homeostasis and glycemic control in patients with type 2 diabetes. Over the past 20 years, a breadth of studies has been conducted in humans and rodents aimed to identify the regulatory nodes responsible for surgical remission of type 2 diabetes. The review herein discusses central mechanisms of type 2 diabetes remission associated with weight loss and surgical modification of the gastrointestinal tract.