Renal Angiomyolipoma: A Diagnostic and Therapeutic Challenge

• Alejandro Bellas-Pereira ^[1] ; María de los Ángeles Betancor Santos ^[2] ; Alba López Castelló ^[3] ; María Pérez Costas ^[3] ; Milagros Otero-García ^[3] ; Pilar San Miguel-Fraile ^[2] ; Patricia Domínguez-Aristegui ^[3] ; José Antonio Ortiz-Rey ^[2]
  1. [1] Urology Department, Álvaro Cunqueiro Hospital, Vigo
  2. [2] Pathology Department, Álvaro Cunqueiro Hospital, Vigo
  3. [3] Radiology Department, Álvaro Cunqueiro Hospital, Vigo

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• Localización: Archivos españoles de urología, ISSN 0004-0614, Tomo 76, Nº. 2, 2023, págs. 169-174
• Idioma: inglés
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• Resumen

  • Background: Angiomyolipomas (AML) represent less than 10% of renal tumours. They are most often detected incidentally during imaging tests, but there are several histological variants that pose difficulties in the radiological differential diagnosis. Their identification should allow the loss of renal parenchyma due to embolization or radical surgery to be prevented.

    Methods: Retrospective study of patients undergoing kidney surgery with post-surgical pathological diagnosis of AML at the Álvaro Cunqueiro Hospital (2016–2021). Patients with a radiological diagnosis of AML who underwent surgery based on clinical criteria were excluded.

    Results: 18 patients were registered, allowing for the assessment of 18 renal tumours. All of the cases were diagnosed incidentally. Preoperative radiological diagnosis was: 9 lesions suggestive of renal cell carcinoma (RCC) (50%), 7 cases suggestive of RCC vs. AML (38.9%) and 2 lesions suggestive of AML vs. retroperitoneal liposarcoma (11.1%). Histological variants of AML were found in 61.1% of cases (n = 11). The most widely used surgical technique was partial nephrectomy, in 66.67% of cases.

    Conclusions: The radiological differential diagnosis of AML, and particularly its variants, with malignant lesions have important limitations either due to the predominance or scarcity of any of the AML components. Some cases can also pose difficulties at the histological level. This fact highlights the importance of the specialization of uroradiologists and uropathologists and the performance of kidney-sparing therapeutic techniques.