The regulation roles of miRNAs in Helicobacter pylori infection
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Ting Tong [1] ; You Zhou [1] ; Qiaoling Huang [1] ; Cui Xiao [1] ; Qinqin Bai [1] ; Bo Deng [1] ; Lili Chen [1]
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[1] University of South China
University of South China
China
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- Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 25, Nº. 7 (July), 2023, págs. 1929-1939
- Idioma: inglés
- Texto completo no disponible (Saber más ...)
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Resumen
Helicobacter pylori is a kind of Gram-negative bacteria that parasitizes on human gastric mucosa. Helicobacter pylori infection is very common in human beings, which often causes gastrointestinal diseases, including chronic gastritis, duodenal ulcer and gastric cancer. MicroRNAs are a group of endogenous non-coding single stranded RNAs, which play an important role in cell proliferation, differentiation, autophagy, apoptosis and inflammation. In recent years, relevant studies have found that the expression of microRNA is changed after Helicobacter pylori infection, and then regulate the biological process of host cells. This paper reviews the regulation role of microRNAs on cell biological behavior through different signal pathways after Helicobacter pylori infection.
