A nonlinear model of Brownian motion is developed in a three-dimensional quantum vacuum defined by a variable quantum vacuum energy density corresponding to processes of creation/annihilation of virtual particles. In this model, the polarization of the quantum vacuum determined by a perturbative fluctuation of the quantum vacuum energy density associated with a fluctuating viscosity, which mimics the action of dark matter, emerges as the fundamental entity which generates the Brownian motion.
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