There has been a study conducted to determine the possibility of using Na-thiosulphate to neutralize forages with an increased content of Cd, Pb and other toxic elements. It has been discovered that rats fed for two months with a diet including special fodder mixed with compounds of Cd (0.91 mg/kg), Pb (18.3 mg/kg) and Na-thiosulphate (2-10 g/kg) reduced by two times the accumulation of metals as compared to animals receiving only compounds of Cd and Pb. Animals fed with Cd and Pb compounds accumulated these metals in different organs, and had increased levels of γ-glutamiltransferase and metallothioneines in liver and kidneys. There was also observed a decrease of SH-concentrations in blood serum and the activity of porfibilinogensynthase, and a minor depression of levels of haemoglobin as compared to the control group.
Na-thiosulphate also caused a remarkable gain of rat and sheep biomass and reduced the assimilation of Hg by sheep in conditions of mercuryenrichment biogeochemical provinces. It was not discovered some effect of Na-thiosulphate on level As and Sb in animal organism.
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