A review of the literature on antimicrobial preservatives: Definition, properties, classification, safety, side effects and antimicrobial effectiveness testing

• Al-Rubaye , Imad M. Malik ^[1]
  1. [1] Department of Pharmacy, Pharmaceutical Chemistry, Baghdad College for Medical
• Localización: Atena Journal of Public Health, ISSN-e 2695-5911, Volumen 4, 2022, 17 págs.
• Idioma: inglés
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• Resumen

  • Antimicrobial preservatives are excipients that are utilized in both sterile & non-sterile pharmaceutical products that are given in several doses. Antimicrobial preservatives are mainly utilized to prevent the growth of germs that may arise throughout the course of a product's uses. It is necessary to determine the efficiency of antimicrobial preservatives in the case of certain excipients. It is discussed in this article the most important aspects to consider when selecting preservatives, the principles of the preservative effectiveness test, and the relevance of regulatory requirements for preservative effectiveness testing in the practice of medicine. Antimicrobial effectiveness testing is required to establish the efficacy of preservative systems in multidose products that are carried out by the manufacturer.