Pharmaceutical care improves medication adherence and quality of life in type 2 diabetes mellitus

• Angélica Marchesi Lira-Meriguete ^[1] ; Mayara Paes Santos ^[1] ; Viviam Cerqueira de Souza Viana ^[2] ; Nadmy Arrivabene Zavaris Gonçalves ^[1] ; Francine Costa Guimarães ^[1] ; Lorena Rocha Ayres ^[1] ; Daniela Amorim Melgaço Guimarães do Bem ^[1] ; Rita de Cássia Ribeiro Gonçalves ^[1]
  1. [1] Universidade Federal do Espírito Santo

     Universidade Federal do Espírito Santo

     Brasil

     
  2. [2] Graduate Program in Pharmaceutical Services, University of Vila Velha, Espírito Santo, Brazil
• Localización: Pharmacy Practice (Granada), ISSN-e 1886-3655, Vol. 21, Nº. 4, 2023 (Ejemplar dedicado a: Oct-Dec)
• Idioma: inglés
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• Resumen

  • Aims: This study aimed to evaluate whether pharmacotherapeutic follow-up in patients with T2DM in primary care interferes in metabolic control, cardiovascular risk, medication adherence and quality of life. Methods: A prospective clinical study was conducted at two Primary Health Units in Vitória, Espírito Santo, Brazil with 75 patients with T2DM between 40 and 70 years old. The parameters of metabolic control evaluated included fasting blood glucose, HbA1c, triglyceride/HDL-c and total cholesterol/HDL-c ratio. The cardiovascular risk was calculated based on the Framingham risk score. Adherence to medication was measured using the Brief Medication Questionnaire and quality of life was evaluated by applying the World Health Organization Quality of Life-Bref. Results: After the follow-up, there was a significant decreasing in cardiovascular risk (p=0.048) and total cholesterol/HDL-c ratio (p=0.024) and a discrete improvement in fast glucose and HbA1c levels. The quality of life scores increased for all domains (p<0.0001) and the treatment adherence also improved with 12.00% of the patients classified as low adherence in the final time, against 41.33% before the meetings. Conclusion: These results show the proposed pharmacotherapeutic follow-up influenced positively cardiovascular risk, adherence to therapy and quality of life in all domains, and, therefore, may contribute to delay the onset of the main chronic complications of the disease.