Azken urteotan, bektore ez-biral lipidikoak oso aintzatetsiak izan dira COVID gaixotasunerako garatu diren txerto berriei esker. Hori dela eta, artikulu honetan, gure ikerketa-taldean lantzen ditugun bi bektore ez-biral motak azaltzen ditugu: niosomak eta partikula lipidikoak. Horien ekoizpenerako mikrofluidika eta sonikazio metodoak erabiltzen ditugu, eta aipatutako formulazioen aktibitatean metodo bakoitzak duen eragina erakusten dugu. Azkenik, formulazio berri horien oraingo eta etorkizuneko aplikazioak aipatzen ditugu, medikuntzaren arloan ekarri ditzaketen aurrerapenak azpimarratuz
In recent years, non-viral lipid vectors have gained important recognition thanks to the new vaccines that have been developed for COVID. For this reason, in this article we wanted to refer to the two types of vectors that we work with in our research group, niosomes and lipid particles. Focusing on their production processes, we will show the importance of microjluidic and sonicator methods in the activity of these formulations. Finally, we will mention the present and future applications of these new formulations, highlighting their potential to become one of the major advances in medicine.
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