Advances in total synthesis of alternaric acid: An anti-fungal and phytotoxic natural product

• SAJJAD AHMAD ^[1] ; MUHAMMAD YOUSAF ^[2] ; AMEER FAWAD ZAHOOR ^[2] ; MATLOOB AHMAD ^[2] ; ZULFIQAR ALI KHAN ^[2] ; MUHAMMAD ARSLAN RASHID ^[2]
  1. [1] University of Engineering and Technology Lahore Department of Chemistry
  2. [2] Government College University Institute of Chemistry
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 62, Nº. 1, 2017, págs. 3315-3321
• Idioma: inglés
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• Resumen

  • Alternaric acid is characterized as 1,4-diene, possessing (E)-1,2-disubstituted alkene known for nanomolar phytotoxic and antifungal activities. This article highlights the major synthetic approaches attempted towards the total synthesis of alternaric acid reported by three groups (Ichihara & coworkers, Trost & coworkers and Johnson and Slade) which involved novel pathways for the rapid construction of this functionalized natural molecule.