Resumen de Secondary metabolites from pachystroma longifolium (nees) i. M. Johnst (euphorbiaceae) and evaluation of its extracts as cathepsins inhibitors

Dayane de Cássia Galvão, Carolina Torres Moraes, Bárbara Juliana Pinheiro Borges, Weverson Cavalcante Cardoso, Jean Paulo De Andrade, Pedro Mitsuo Takahashi, Paulo Cezar Vieira, Warley de Souza Borges

• In this work, four secondary metabolites were isolated from leaves of Pachystroma longifolium (Euphorbiaceae): loliolide, gallic acid, methyl protocatechuate and ethyl gallate. Their structures were established by physical and spectroscopic methods. The extracts of P. longifolium and the purified compounds were tested as cathepsins inhibitors and the extracts were active.