Resumen de Rapid method of friedel-crafts alkylation of phloroglucinol by microwave in dry media and reusable catalyst

Alejandra P Vergara, Javier A Contreras, Mauricio E Osorio, Marcela A Carvajal

• A new rapid and efficient method for the synthesis of a series of alkylated phloroglucinols using conventional microwave is reported 4 phloroglucinol derivatives (4, 5, 6 and 7) were synthesized with good yields (~50%) by a Friedel-Crafts reaction through an Electrophilic Aromatic Substitution mechanism between geraniol/prenol and phloroglucinol, using reusable SiO2 and AgNO3 as the best catalyst tested without solvents under microwave irradiation.